Transcutaneous contrast-enhanced sonography for diagnosis of sentinel lymph nodes in early breast cancer
G. G. Khakimova,
I. V. Reshetov,
A. D. Zikiryakhodzhaev,
M. V. Starkova,
Sh. G. Khakimova,
V. O. Timoshkin https://doi.org/10.17650/2782-3202-2024-4-4-111-118
Abstract
Disease stage and especially condition of the sentinel lymph node (SLN) assessed in patients with breast cancer prior to treatment are among the most important prognostic factors. SLN is the first lymph node in the regional lymph node system receiving lymph outflow from the primary tumor. SLN biopsy with blue dye gradually replaced traditional axillary lymph node dissection as the standard of treatment of early breast cancer. In the recent years, technique of contrast-enhanced sonography with microbubble contrast agents for examination of the lymph system has been studied both in animal and human trials.
Aim of the review is to investigate the effectiveness of transcutaneous contrast-enhanced sonography of the SLN for biopsy and for diagnosis of metastatic SLNs using methylene blue as the standard in patients with early breast cancer.
About the Authors
G. G. Khakimova
Tashkent city branch of the Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology, Ministry of Health of Republic of Uzbekistan; Tashkent Pediatric Medical Institute
Uzbekistan
Uzbekistan
Gulnoz Golibovna Khakimova
1 Bogiston St., Tashkent, 100070
223 Bogishamol St., Tashkent, 100140
I. V. Reshetov
L.L. Levshin Institute of Cluster Oncology, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University); N.V. Sklifosovsky Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Russian Federation
Russian Federation
Bld. 2, 8 Trubetskaya St., Moscow, 119991
Bld. 2, 11 Rossolimo St., Moscow, 119021
A. D. Zikiryakhodzhaev
P.A. Hertsen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre, Ministry of Health of Russia; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University); Peoples’ Friendship University of Russia n. a. Patrice Lumumba
Russian Federation
Russian Federation
3 2ndBotkinskiy Proezd, Moscow, 125284
Bld. 2, 8 Trubetskaya St., Moscow, 119991
6 Miklukho-Maklaya St., Moscow, 117198
M. V. Starkova
P.A. Hertsen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre, Ministry of Health of Russia
Russian Federation
Russian Federation
3 2ndBotkinskiy Proezd, Moscow 125284
Sh. G. Khakimova
N.V. Sklifosovsky Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University); P.A. Hertsen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre, Ministry of Health of Russia
Russian Federation
Russian Federation
Bld. 2, 11 Rossolimo St., Moscow 119021
3 2ndBotkinskiy Proezd, Moscow 125284
V. O. Timoshkin
P.A. Hertsen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre, Ministry of Health of Russia
Russian Federation
Russian Federation
3 2ndBotkinskiy Proezd, Moscow 125284
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Review
For citations:
Khakimova G.G., Reshetov I.V., Zikiryakhodzhaev A.D., Starkova M.V., Khakimova Sh.G., Timoshkin V.O. Transcutaneous contrast-enhanced sonography for diagnosis of sentinel lymph nodes in early breast cancer. MD-Onco. 2024;4(4):111-118. (In Russ.) https://doi.org/10.17650/2782-3202-2024-4-4-111-118
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