Surgical strategy in BRCA-associated breast cancer. Clinical case
https://doi.org/10.17650/2782-3202-2021-1-1-87-92
Abstract
BRCA1 and BRCA2 genes mutations increase the risk of breast and ovarian cancer. Primary diagnosis of ovarian cancer is a complicated task due to the lack of effective screening programs, in this regard, medical and genetic counseling of patients with a family history is one of the important steps to develop an optimal strategy for the management of patients. In this article is presented an analysis of a clinical case of a patient with bilateral metachronous breast and ovarian cancer with a detected germinal mutation
5382insС in the BRCA1 gene.
About the Authors
L. N. Lyubchenko
I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia;
National Medical Research Center of Radiology, Ministry of Health of Russia
Russian Federation
Russian Federation
Bld. 2, 8 Trubetskaya St., Moscow 119991, Russia
4 Koroleva St., Obninsk 249036, Russia
E. E. Zelenova
National Medical Research Center of Radiology, Ministry of Health of Russia
Russian Federation
Russian Federation
4 Koroleva St., Obninsk 249036, Russia
A. A. Suglobova
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
24 Kashirskoe Shosse, Moscow 115478, Russia
K. I. Zhordaniya
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
24 Kashirskoe Shosse, Moscow 115478, Russia
M. M. Davydov
I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia;
Clinical Hospital “Lapino” of the “Mother and Child” Group of companies
Russian Federation
Russian Federation
Bld. 2, 8 Trubetskaya St., Moscow 119991, Russia
111 1st Uspenskoe Shosse, Lapino, Moscow region 143081, Russia
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Review
For citations:
Lyubchenko L.N., Zelenova E.E., Suglobova A.A., Zhordaniya K.I., Davydov M.M. Surgical strategy in BRCA-associated breast cancer. Clinical case. MD-Onco. 2021;1(1):87-92. (In Russ.) https://doi.org/10.17650/2782-3202-2021-1-1-87-92
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