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Patient noncompliance as the cause of skin toxicity in capecitabine therapy

https://doi.org/10.17650/2782-3202-2022-2-3-55-58

Abstract

When using capecitabine, manifestations of toxicity in the form of palmar-plantar dysesthesia, redness, excessive sensitivity and peeling of the skin of the palms and feet are well known. However, in the scientific literature available to us, we did not find a single case of skin toxicity with capecitabine, in contrast to targeted therapy, for which skin manifestations are very characteristic. The dermal toxicity described in this paper developed as a result of patient noncompliance. These side effects reduced the adherence to therapy: the next courses of chemotherapy were postponed.

About the Authors

L. M. Kogoniya
M.F. Vladimirsky Moscow Region Scientific Research Clinical Institute; “Clinic K+31” JSC
Russian Federation

Lali M. Kogoniya

61/2 Shchepkina St., Moscow 129110, 

Bld. 4, 42 Lobachevskogo St., Moscow 119415

 



K. E. Borisov
“Clinic K+31” JSC
Russian Federation

Bld. 4, 42 Lobachevskogo St., Moscow 119415



K. I. Ershova
“Clinic K+31” JSC
Russian Federation

Bld. 4, 42 Lobachevskogo St., Moscow 119415



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Review

For citations:


Kogoniya L.M., Borisov K.E., Ershova K.I. Patient noncompliance as the cause of skin toxicity in capecitabine therapy. MD-Onco. 2022;2(3):55-58. (In Russ.) https://doi.org/10.17650/2782-3202-2022-2-3-55-58

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ISSN 2782-3202 (Print)
ISSN 2782-6171 (Online)