Perforation of the colon, diffuse septic fibrinous peritonitis in a patient with diffuse large B-cell lymphoma. Clinical observation
https://doi.org/10.17650/2782-3202-2021-1-1-51-54
Abstract
Perforation of a hollow organ with development of peritonitis is a known complication of lymphomas often occurring during diagnosis or therapy. Frequency of perforations of the gastrointestinal tract in patients with lymphomas is 9 %. Presence of a perforation complicates treatment and can worsen disease prognosis.
A clinical case of a patient with diffuse large B-cell lymphoma complicated by surgical pathology and infection is presented: perforation of the transverse colon, fibrinous septic peritonitis were detected during a diagnostic procedure (prior to morphological verification of the diagnosis), and COVID-associated pneumonia developed later. The selected treatment tactics despite the volume of surgical intervention and presence of infectious complications allowed to achieve improvement of the patient’s condition.
About the Authors
M. M. DavydovRussian Federation
111 1st Uspenskoe Shosse, Lapino, Moscow region 143081, Russia
P. A. Zeynalova
Russian Federation
111 1st Uspenskoe Shosse, Lapino, Moscow region 143081, Russia
E. V. Glukhov
Russian Federation
111 1st Uspenskoe Shosse, Lapino, Moscow region 143081, Russia
Yu. E. Ryabukhina
Russian Federation
111 1st Uspenskoe Shosse, Lapino, Moscow region 143081, Russia
O. I. Timofeeva
Russian Federation
111 1st Uspenskoe Shosse, Lapino, Moscow region 143081, Russia
A. A. Filatov
Russian Federation
111 1st Uspenskoe Shosse, Lapino, Moscow region 143081, Russia
M. S. Shogenov
Russian Federation
111 1st Uspenskoe Shosse, Lapino, Moscow region 143081, Russia
A. G. Zhukov
Russian Federation
111 1st Uspenskoe Shosse, Lapino, Moscow region 143081, Russia
V. E. Gruzdev
Russian Federation
111 1st Uspenskoe Shosse, Lapino, Moscow region 143081, Russia
M. A. Anisimov
Russian Federation
111 1st Uspenskoe Shosse, Lapino, Moscow region 143081, Russia
References
1. Amore F., Brincker H., Gronbaek K. et al. Non-Hodgkin’s lymphoma of the gastrointestinal tract: a populationbased analysis of incidence, geographic distribution, clinicopathologic presentation features, and prognosis. Danish Lymphoma Study Group. J Clin Oncol 1994;12(8):1673–84. DOI: 10.1200/JCO.1994.12.8.1673.
2. Amer M.H., el-Akkad S. Gastrointestinal lymphoma in adults: clinical features and management of 300 cases. Gastroenterolоgy 1994;106(4):846–58. DOI: 10.1016/0016-5085(94)90742-0.
3. Otter R., Bieger R., Kluin P.M. et al. Primary gastrointestinal non-Hodgkin’s lymphoma in a population-based registry. Br J Cancer 1989;60(5):745–50. DOI: 10.1038/bjc.1989.351.
4. Gou H.F., Zang J., Jiang M. et al. Clinical prognostic analysis of 116 patients with primary intestinal non-Hodgkin lymphoma. Med Oncol 2012;29(1):227–34. DOI: 10.1007/s12032-010-9783-x.
5. Vaidya R., Habermann T.M., Donohue J.H. et al. Bowel perforation in intestinal lymphoma: incidenceand clinical features. Ann Oncol 2013;24(9):2439–43. DOI: 10.1093/annonc/mdt188.
6. Kako S., Oshima K., Sato M. et al. Clinical outcome in patients with smallintestinalnon-Hodgkin lymphoma. Leuk Lymphoma 2009;50(10):1618–24. DOI: 10.1080/10428190903147629.
7. Doolabh N., Anthony T., Simmang C. et al. Primary colonic lymphoma. J Surg Oncol 2000;74(4):257–62. DOI: 10.1002/1096-9098(200008)74:4<257::aid-jso3>3.0.co;2-u.
8. Bairey O., Ruchlemer R., Shpilberg O. NonHodgkin’s lymphomas of the colon. Isr Med Assoc J 2006;8(12):832–5. PMID: 17214096.
Review
For citations:
Davydov M.M., Zeynalova P.A., Glukhov E.V., Ryabukhina Yu.E., Timofeeva O.I., Filatov A.A., Shogenov M.S., Zhukov A.G., Gruzdev V.E., Anisimov M.A. Perforation of the colon, diffuse septic fibrinous peritonitis in a patient with diffuse large B-cell lymphoma. Clinical observation. MD-Onco. 2021;1(1):51-54. (In Russ.) https://doi.org/10.17650/2782-3202-2021-1-1-51-54